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Analysis of Huntington’s Disease Modifiers Using the Hyperbolic Mapping of the Protein Interaction Network

Huntington’s disease (HD) is caused by the production of a mutant huntingtin (HTT) with an abnormally long poly-glutamine (polyQ) tract, forming aggregates and inclusions in neurons. Previous work by us and others has shown that an increase or decrease in polyQ-triggered aggregates can be passive si...

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Detalles Bibliográficos
Autores principales:	Vagiona, Aimilia-Christina, Mier, Pablo, Petrakis, Spyros, Andrade-Navarro, Miguel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144261/ https://www.ncbi.nlm.nih.gov/pubmed/35628660 http://dx.doi.org/10.3390/ijms23105853

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