Inclusion of a Phytomedicinal Flavonoid in Biocompatible Surface-Modified Chylomicron Mimic Nanovesicles with Improved Oral Bioavailability and Virucidal Activity: Molecular Modeling and Pharmacodynamic Studies

Morin hydrate (MH) is a widely-used Asian phytomedicinal flavonoid with a wide range of reported therapeutic activities. However, MH has limited oral bioavailability due to its low aqueous solubility and intestinal permeability, which in turn hinders its potential antiviral activity. The study repor...

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Detalles Bibliográficos
Autores principales: Zakaria, Mohamed Y., Georghiou, Paris E., Banoub, Joseph H., Beshay, Botros Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144278/
https://www.ncbi.nlm.nih.gov/pubmed/35631491
http://dx.doi.org/10.3390/pharmaceutics14050905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144278/
https://www.ncbi.nlm.nih.gov/pubmed/35631491
http://dx.doi.org/10.3390/pharmaceutics14050905

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