Inhibition of Polo-like Kinase 1 by HMN-214 Blocks Cell Cycle Progression and Inhibits Neuroblastoma Growth

Polo-like kinase 1 (PLK1) is an essential cell cycle mitotic kinase component that plays an important role in cell cycle progression and has been reported to be involved in various cancers, including neuroblastoma (NB). PLK1 also regulates G2/M transition, chromosomal segregation, spindle assembly m...

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Detalles Bibliográficos
Autores principales: Chilamakuri, Rameswari, Rouse, Danielle Crystal, Agarwal, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144399/
https://www.ncbi.nlm.nih.gov/pubmed/35631350
http://dx.doi.org/10.3390/ph15050523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144399/
https://www.ncbi.nlm.nih.gov/pubmed/35631350
http://dx.doi.org/10.3390/ph15050523

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