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Methylene Blue Is a Nonspecific Protein–Protein Interaction Inhibitor with Potential for Repurposing as an Antiviral for COVID-19

We have previously identified methylene blue, a tricyclic phenothiazine dye approved for clinical use for the treatment of methemoglobinemia and for other medical applications as a small-molecule inhibitor of the protein–protein interaction (PPI) between the spike protein of the SARS-CoV-2 coronavir...

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Detalles Bibliográficos
Autores principales: Chuang, Sung-Ting, Papp, Henrietta, Kuczmog, Anett, Eells, Rebecca, Condor Capcha, Jose M., Shehadeh, Lina A., Jakab, Ferenc, Buchwald, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144480/
https://www.ncbi.nlm.nih.gov/pubmed/35631447
http://dx.doi.org/10.3390/ph15050621