Overcoming Hypoxia-Induced Drug Resistance via Promotion of Drug Uptake and Reoxygenation by Acousto–Mechanical Oxygen Delivery

Hypoxia-induced drug resistance (HDR) is a critical issue in cancer therapy. The presence of hypoxic tumor cells impedes drug uptake and reduces the cytotoxicity of chemotherapeutic drugs, leading to HDR and increasing the probability of tumor recurrence and metastasis. Microbubbles, which are used...

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Detalles Bibliográficos
Autores principales: Ho, Yi-Ju, Thao, Dinh Thi, Yeh, Chih-Kuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144555/
https://www.ncbi.nlm.nih.gov/pubmed/35631488
http://dx.doi.org/10.3390/pharmaceutics14050902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144555/
https://www.ncbi.nlm.nih.gov/pubmed/35631488
http://dx.doi.org/10.3390/pharmaceutics14050902

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