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Rational Design of a Skin- and Neuro-Attenuated Live Varicella Vaccine: A Review and Future Perspectives

Primary varicella-zoster virus (VZV) infection causes varicella, which remains a prominent public health concern in children. Current varicella vaccines adopt the live-attenuated Oka strain, vOka, which retains the ability to infect neurons, establish latency and reactivate, leading to vaccine-assoc...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Pan, Dequan, Cheng, Tong, Zhu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144592/
https://www.ncbi.nlm.nih.gov/pubmed/35632591
http://dx.doi.org/10.3390/v14050848