Intranasal Immunization with Zika Virus Envelope Domain III-Flagellin Fusion Protein Elicits Systemic and Mucosal Immune Responses and Protection against Subcutaneous and Intravaginal Virus Challenges

Zika virus (ZIKV) infections in humans are mainly transmitted by the mosquito vectors, but human-to-human sexual transmission is also another important route. Developing a ZIKV mucosal vaccine that can elicit both systemic and mucosal immune responses is of particular interest. In this study, we con...

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Detalles Bibliográficos
Autores principales: Chen, Chi-Hsun, Chen, Chung-Chu, Wang, Wei-Bo, Lionel, Vania, Liu, Chia-Chyi, Huang, Li-Min, Wu, Suh-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144594/
https://www.ncbi.nlm.nih.gov/pubmed/35631599
http://dx.doi.org/10.3390/pharmaceutics14051014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144594/
https://www.ncbi.nlm.nih.gov/pubmed/35631599
http://dx.doi.org/10.3390/pharmaceutics14051014

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