Deletion of the CTRL2 Insulator in HSV-1 Results in the Decreased Expression of Genes Involved in Axonal Transport and Attenuates Reactivation In Vivo

HSV-1 is a human pathogen that establishes a lifelong infection in the host. HSV-1 is transported by retrograde axonal transport to sensory neurons in the peripheral nervous system where latent viral genomes can reactivate. The resulting virus travels via anterograde axonal transport to the peripher...

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Detalles Bibliográficos
Autores principales: Singh, Pankaj, Collins, Matthew F., Johns, Richard N., Manuel, Kayley A., Ye, Ziyun A., Bloom, David C., Neumann, Donna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144644/
https://www.ncbi.nlm.nih.gov/pubmed/35632655
http://dx.doi.org/10.3390/v14050909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144644/
https://www.ncbi.nlm.nih.gov/pubmed/35632655
http://dx.doi.org/10.3390/v14050909

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