Physiologically-Based Pharmacokinetics Modeling for Hydroxychloroquine as a Treatment for Malaria and Optimized Dosing Regimens for Different Populations

Malaria is a severe parasite infectious disease with high fatality. As one of the approved treatments of this disease, hydroxychloroquine (HCQ) lacks clinical administration guidelines for patients with special health conditions and co-morbidities. This may result in improper dosing for different po...

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Detalles Bibliográficos
Autores principales: Zhai, Jingchen, Ji, Beihong, Cai, Lianjin, Liu, Shuhan, Sun, Yuchen, Wang, Junmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144775/
https://www.ncbi.nlm.nih.gov/pubmed/35629219
http://dx.doi.org/10.3390/jpm12050796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144775/
https://www.ncbi.nlm.nih.gov/pubmed/35629219
http://dx.doi.org/10.3390/jpm12050796

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