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Physiologically-Based Pharmacokinetics Modeling for Hydroxychloroquine as a Treatment for Malaria and Optimized Dosing Regimens for Different Populations
Malaria is a severe parasite infectious disease with high fatality. As one of the approved treatments of this disease, hydroxychloroquine (HCQ) lacks clinical administration guidelines for patients with special health conditions and co-morbidities. This may result in improper dosing for different po...
Autores principales: | Zhai, Jingchen, Ji, Beihong, Cai, Lianjin, Liu, Shuhan, Sun, Yuchen, Wang, Junmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144775/ https://www.ncbi.nlm.nih.gov/pubmed/35629219 http://dx.doi.org/10.3390/jpm12050796 |
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