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Functionalized Nitroimidazole Scaffold Construction and Their Pharmaceutical Applications: A 1950–2021 Comprehensive Overview

Nitroimidazole represents one of the most essential and unique scaffolds in drug discovery since its discovery in the 1950s. It was K. Maeda in Japan who reported in 1953 the first nitroimidazole as a natural product from Nocardia mesenterica with antibacterial activity, which was later identified a...

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Detalles Bibliográficos
Autores principales: Gupta, Ria, Sharma, Sumit, Singh, Rohit, Vishwakarma, Ram A., Mignani, Serge, Singh, Parvinder Pal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144801/
https://www.ncbi.nlm.nih.gov/pubmed/35631389
http://dx.doi.org/10.3390/ph15050561