Engineering defensin α‐helix to produce high‐affinity SARS‐CoV‐2 spike protein binding ligands

The binding of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) spike protein to the angiotensin‐converting enzyme 2 (ACE2) receptor expressed on the host cells is a critical initial step for viral infection. This interaction is blocked through competitive inhibition by soluble ACE2 prot...

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Detalles Bibliográficos
Autores principales: Fernandes, Leonardo Antônio, Gomes, Anderson Albino, Guimarães, Beatriz Gomes, de Lourdes Borba Magalhães, Maria, Ray, Partha, da Silva, Gustavo Felippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Full‐length Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144876/
https://www.ncbi.nlm.nih.gov/pubmed/35634778
http://dx.doi.org/10.1002/pro.4355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144876/
https://www.ncbi.nlm.nih.gov/pubmed/35634778
http://dx.doi.org/10.1002/pro.4355

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