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The Role of Cryotherapy in Vitreous Concentrations of Topotecan Delivered by Episcleral Hydrogel Implant

Transscleral diffusion delivery of chemotherapy is a promising way to reach the vitreal seeds of retinoblastoma, the most common intraocular malignancy in childhood. In this in vivo study, the delivery of topotecan via lens-shaped, bi-layered hydrogel implants was combined with transconjunctival cry...

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Detalles Bibliográficos
Autores principales: Kodetova, Martina, Hobzova, Radka, Sirc, Jakub, Uhlik, Jiri, Dunovska, Katerina, Svojgr, Karel, Cocarta, Ana-Irina, Felsoova, Andrea, Slanar, Ondrej, Sima, Martin, Kozak, Igor, Pochop, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144907/
https://www.ncbi.nlm.nih.gov/pubmed/35631489
http://dx.doi.org/10.3390/pharmaceutics14050903