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A Straightforward Approach to Synthesize 7-Aminocephalosporanic Acid In Vivo in the Cephalosporin C Producer Acremonium chrysogenum

The pharmaceutical industry has developed various highly effective semi-synthetic cephalosporins, which are generated by modifying the side chains of the core molecule 7-aminocephalosporanic acid (7-ACA). In industrial productions, the 7-ACA nucleus is obtained in vitro from cephalosporin C (CPC) by...

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Detalles Bibliográficos
Autores principales: Lin, Xuemei, Lambertz, Jan, Dahlmann, Tim A., Nowaczyk, Marc M., König, Burghard, Kück, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144927/
https://www.ncbi.nlm.nih.gov/pubmed/35628706
http://dx.doi.org/10.3390/jof8050450