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Restoration of Vision and Retinal Responses After Adeno-Associated Virus–Mediated Optogenetic Therapy in Blind Dogs

PURPOSE: Optogenetic gene therapy to render remaining retinal cells light-sensitive in end-stage retinal degeneration is a promising strategy for treatment of individuals blind because of a variety of different inherited retinal degenerations. The clinical trials currently in progress focus on deliv...

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Detalles Bibliográficos
Autores principales: Nikonov, Sergei, Aravand, Puya, Lyubarsky, Arkady, Nikonov, Roman, Luo, Angela J., Wei, Zhangyong, Maguire, Albert M., Phelps, Nicholas T., Shpylchak, Ivan, Willett, Keirnan, Aleman, Tomas S., Huckfeldt, Rachel M., Ramachandran, Pavitra S., Bennett, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145127/
https://www.ncbi.nlm.nih.gov/pubmed/35604672
http://dx.doi.org/10.1167/tvst.11.5.24