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Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors

Acetylcholinesterase (AChE) is one of the classical targets in the treatment of Alzheimer’s disease (AD). Inhibition of AChE slows down the hydrolysis of acetycholine and increases choline levels, improving the cognitive function. The achieved success of plant-based natural drugs acting as AChE inhi...

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Detalles Bibliográficos
Autores principales: Atanasova, Mariyana, Dimitrov, Ivan, Ivanov, Stefan, Georgiev, Borislav, Berkov, Strahil, Zheleva-Dimitrova, Dimitrina, Doytchinova, Irini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145144/
https://www.ncbi.nlm.nih.gov/pubmed/35630613
http://dx.doi.org/10.3390/molecules27103139