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Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors
Acetylcholinesterase (AChE) is one of the classical targets in the treatment of Alzheimer’s disease (AD). Inhibition of AChE slows down the hydrolysis of acetycholine and increases choline levels, improving the cognitive function. The achieved success of plant-based natural drugs acting as AChE inhi...
Autores principales: | Atanasova, Mariyana, Dimitrov, Ivan, Ivanov, Stefan, Georgiev, Borislav, Berkov, Strahil, Zheleva-Dimitrova, Dimitrina, Doytchinova, Irini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145144/ https://www.ncbi.nlm.nih.gov/pubmed/35630613 http://dx.doi.org/10.3390/molecules27103139 |
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