Facile Synthesis of Tricyclic 1,2,4-Oxadiazolines-Fused Tetrahydro-Isoquinolines from Oxime Chlorides with 3,4-Dihydroisoquinoline Imines

A mild and efficient strategy for the synthesis of tricyclic 1,2,4-oxadiazolines-fused tetrahydro-isoquinolines derivatives via [3 + 2] cycloaddition reaction is reported. The reactions provided the functionalized tricyclic 1,2,4-oxadiazolines in high yields (up to 96%). This protocol is simple and...

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Detalles Bibliográficos
Autores principales: Wang, Kaikai, Li, Yanli, Zhang, Wei, Chen, Rongxiang, Ma, Xueji, Wang, Mingyue, Zhou, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145198/
https://www.ncbi.nlm.nih.gov/pubmed/35630538
http://dx.doi.org/10.3390/molecules27103064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145198/
https://www.ncbi.nlm.nih.gov/pubmed/35630538
http://dx.doi.org/10.3390/molecules27103064

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