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Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases MUTYH and hOGG1 in Colorectal Cancer Patients

Oxidative stress, oxidative DNA damage and resulting mutations play a role in colorectal carcinogenesis. Impaired equilibrium between DNA damage formation, antioxidant status, and DNA repair capacity is responsible for the accumulation of genetic mutations and genomic instability. The lesion-specifi...

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Detalles Bibliográficos
Autores principales: Kavec, Miriam J., Urbanova, Marketa, Makovicky, Pavol, Opattová, Alena, Tomasova, Kristyna, Kroupa, Michal, Kostovcikova, Klara, Siskova, Anna, Navvabi, Nazila, Schneiderova, Michaela, Vymetalkova, Veronika, Vodickova, Ludmila, Vodicka, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145200/
https://www.ncbi.nlm.nih.gov/pubmed/35628513
http://dx.doi.org/10.3390/ijms23105704