Diagnostic and Therapeutic Perspectives Associated to Cobalamin-Dependent Metabolism and Transcobalamins’ Synthesis in Solid Cancers

Cobalamin or vitamin B12 (B12) is a cofactor for methionine synthase and methylmalonyl-CoA mutase, two enzymes implicated in key pathways for cell proliferation: methylation, purine synthesis, succinylation and ATP production. Ensuring these functions in cancer cells therefore requires important cob...

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Detalles Bibliográficos
Autores principales: Lacombe, Valentin, Lenaers, Guy, Urbanski, Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145230/
https://www.ncbi.nlm.nih.gov/pubmed/35631199
http://dx.doi.org/10.3390/nu14102058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145230/
https://www.ncbi.nlm.nih.gov/pubmed/35631199
http://dx.doi.org/10.3390/nu14102058

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