Synthesis and Biochemical Evaluation of 8H-Indeno[1,2-d]thiazole Derivatives as Novel SARS-CoV-2 3CL Protease Inhibitors

The COVID-19 pandemic caused by SARS-CoV-2 is a global burden on human health and economy. The 3-Chymotrypsin-like cysteine protease (3CL(pro)) becomes an attractive target for SARS-CoV-2 due to its important role in viral replication. We synthesized a series of 8H-indeno[1,2-d]thiazole derivatives...

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Detalles Bibliográficos
Autores principales: Wu, Jing, Feng, Bo, Gao, Li-Xin, Zhang, Chun, Li, Jia, Xiang, Da-Jun, Zang, Yi, Wang, Wen-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145245/
https://www.ncbi.nlm.nih.gov/pubmed/35630836
http://dx.doi.org/10.3390/molecules27103359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145245/
https://www.ncbi.nlm.nih.gov/pubmed/35630836
http://dx.doi.org/10.3390/molecules27103359

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