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Cloning and Functional Characterization of Two Germacrene A Oxidases Isolated from Xanthium sibiricum

Sesquiterpene lactones (STLs) from the cocklebur Xanthium sibiricum exhibit significant anti-tumor activity. Although germacrene A oxidase (GAO), which catalyzes the production of Germacrene A acid (GAA) from germacrene A, an important precursor of germacrene-type STLs, has been reported, the remain...

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Detalles Bibliográficos
Autores principales: Xie, Dong-Mei, Zhang, Qiang, Xin, Ling-Kai, Wang, Guo-Kai, Liu, Cong-Bin, Qin, Min-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145264/
https://www.ncbi.nlm.nih.gov/pubmed/35630799
http://dx.doi.org/10.3390/molecules27103322