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Increased Ammonium Toxicity in Response to Exogenous Glutamine in Metastatic Breast Cancer Cells

Several cancers, including breast cancers, show dependence on glutamine metabolism. The purpose of the present study was to determine the mechanistic basis and impact of differential glutamine metabolism in nonmetastatic and metastatic murine mammary cancer cells. Universally labeled (13)C(5)-glutam...

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Detalles Bibliográficos
Autores principales: Kiesel, Violet A., Sheeley, Madeline P., Donkin, Shawn S., Wendt, Michael K., Hursting, Stephen D., Teegarden, Dorothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145280/
https://www.ncbi.nlm.nih.gov/pubmed/35629973
http://dx.doi.org/10.3390/metabo12050469