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Self-Nanoemulsifying Drug Delivery System (SNEDDS) of Apremilast: In Vitro Evaluation and Pharmacokinetics Studies

Psoriatic arthritis is an autoimmune disease of the joints that can lead to persistent inflammation, irreversible joint damage and disability. The current treatments are of limited efficacy and inconvenient. Apremilast (APR) immediate release tablets Otezla(®) have 20–33% bioavailability compared to...

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Detalles Bibliográficos
Autores principales: Abushal, Ahad S., Aleanizy, Fadilah S., Alqahtani, Fulwah Y., Shakeel, Faiyaz, Iqbal, Muzaffar, Haq, Nazrul, Alsarra, Ibrahim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145325/
https://www.ncbi.nlm.nih.gov/pubmed/35630561
http://dx.doi.org/10.3390/molecules27103085