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Preparation of DNC Solid Dispersion by a Mechanochemical Method with Glycyrrhizic Acid and Polyvinylpyrrolidone to Enhance Bioavailability and Activity

To exploit aqueous-soluble formulation and improve the anticoccidial activity of 4,4′-dinitrocarbanilide (DNC, active component of nicarbazin), this paper prepared DNC/GA/PVP K30 solid dispersion (SD) with glycyrrhizic acid (GA) and polyvinylpyrrolidone (PVP) K30 by a mechanical ball milling method...

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Detalles Bibliográficos
Autores principales: Lu, Min, Wei, Wei, Xu, Wenhao, Polyakov, Nikolay E., Dushkin, Alexandr V., Su, Weike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145361/
https://www.ncbi.nlm.nih.gov/pubmed/35631919
http://dx.doi.org/10.3390/polym14102037