Design, Semisynthesis, and Estrogenic Activity of Lignan Derivatives from Natural Dibenzylbutyrolactones †

Based on molecular docking studies on the ERα, a series of lignan derivatives (3–16) were designed and semisynthesized from the natural dibenzylbutyrolactones bursehernin (1) and matairesinol dimethyl ether (2). To examine their estrogenic and antiestrogenic potencies, the effects of these compounds...

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Detalles Bibliográficos
Autores principales: López-Rojas, Priscila, Amesty, Ángel, Guerra-Rodríguez, Miguel, Brito-Casillas, Yeray, Guerra, Borja, Fernández-Pérez, Leandro, Estévez-Braun, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145393/
https://www.ncbi.nlm.nih.gov/pubmed/35631411
http://dx.doi.org/10.3390/ph15050585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145393/
https://www.ncbi.nlm.nih.gov/pubmed/35631411
http://dx.doi.org/10.3390/ph15050585

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