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Structural Modeling of TRPA1 Ion Channel—Determination of the Binding Site for Antagonists
TRPA1 is a transmembrane cation channel, one of the most promising targets in the context of respiratory diseases. Its general structure has already been experimentally resolved, but the binding site of TRPA1 antagonists such as HC-030031, a model methylxanthine derivative, remains unknown. The pres...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145427/ https://www.ncbi.nlm.nih.gov/pubmed/35630553 http://dx.doi.org/10.3390/molecules27103077 |