Substituted Purines as High-Affinity Histamine H(3) Receptor Ligands

Continuing with our program to obtain new histamine H(3) receptor (H(3)R) ligands, in this work we present the synthesis, H(3)R affinity and in silico studies of a series of eight new synthetically accessible purine derivatives. These compounds are designed from the isosteric replacement of the scaf...

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Detalles Bibliográficos
Autores principales: Espinosa-Bustos, Christian, Leitzbach, Luisa, Añazco, Tito, Silva, María J., del Campo, Andrea, Castro-Alvarez, Alejandro, Stark, Holger, Salas, Cristian O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145483/
https://www.ncbi.nlm.nih.gov/pubmed/35631399
http://dx.doi.org/10.3390/ph15050573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145483/
https://www.ncbi.nlm.nih.gov/pubmed/35631399
http://dx.doi.org/10.3390/ph15050573

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