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Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC

The compound EACC (ethyl (2-(5-nitrothiophene-2-carboxamido) thiophene-3-carbonyl) carbamate) was recently reported to inhibit fusion of autophagosomes with lysosomes in a reversible manner by inhibiting recruitment of syntaxin 17 to autophagosomes. We report here that this compound also provides a...

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Detalles Bibliográficos
Autores principales: Sandvig, Kirsten, Kavaliauskiene, Simona, Myrann, Anne Grethe, Iversen, Tore Geir, Skotland, Tore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145485/
https://www.ncbi.nlm.nih.gov/pubmed/35622606
http://dx.doi.org/10.3390/toxins14050360