Recent Advances in Translational Pharmacokinetics and Pharmacodynamics Prediction of Therapeutic Antibodies Using Modeling and Simulation

Therapeutic monoclonal antibodies (mAbs) have been a promising therapeutic approach for several diseases and a wide variety of mAbs are being evaluated in clinical trials. To accelerate clinical development and improve the probability of success, pharmacokinetics and pharmacodynamics (PKPD) in human...

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Detalles Bibliográficos
Autores principales: Haraya, Kenta, Tsutsui, Haruka, Komori, Yasunori, Tachibana, Tatsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145563/
https://www.ncbi.nlm.nih.gov/pubmed/35631335
http://dx.doi.org/10.3390/ph15050508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145563/
https://www.ncbi.nlm.nih.gov/pubmed/35631335
http://dx.doi.org/10.3390/ph15050508

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