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An Integrated Approach Reveals DNA Damage and Proteotoxic Stress as Main Effects of Proton Radiation in S. cerevisiae

Proton radiotherapy (PRT) has the potential to reduce the normal tissue toxicity associated with conventional photon-based radiotherapy (X-ray therapy, XRT) because the active dose can be more directly targeted to a tumor. Although this dosimetric advantage of PRT is well known, the molecular mechan...

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Detalles Bibliográficos
Autores principales: Vanderwaeren, Laura, Dok, Rüveyda, Voordeckers, Karin, Vandemaele, Laura, Verstrepen, Kevin J., Nuyts, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145671/
https://www.ncbi.nlm.nih.gov/pubmed/35628303
http://dx.doi.org/10.3390/ijms23105493