Live Vaccination with Blood-Stage Plasmodium yoelii 17XNL Prevents the Development of Experimental Cerebral Malaria

In our work, we aim to develop a malaria vaccine with cross-strain (-species) protection. C57BL/6 mice infected with the P. berghei ANKA strain (PbA) develop experimental cerebral malaria (ECM). In contrast, ECM development is inhibited in infected mice depleted of T cells. The clinical applications...

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Detalles Bibliográficos
Autores principales: Imai, Takashi, Ngo-Thanh, Ha, Suzue, Kazutomo, Shimo, Aoi, Nakamura, Akihiro, Horiuchi, Yutaka, Hisaeda, Hajime, Murakami, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145751/
https://www.ncbi.nlm.nih.gov/pubmed/35632518
http://dx.doi.org/10.3390/vaccines10050762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145751/
https://www.ncbi.nlm.nih.gov/pubmed/35632518
http://dx.doi.org/10.3390/vaccines10050762

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