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A Pharmacometric Model to Predict Chemotherapy-Induced Myelosuppression and Associated Risk Factors in Non-Small Cell Lung Cancer

Chemotherapy often induces severe neutropenia due to the myelosuppressive effect. While predictive pharmacokinetic (PK)/pharmacodynamic (PD) models of absolute neutrophil count (ANC) after anticancer drug administrations have been developed, their deployments to routine clinics have been limited due...

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Detalles Bibliográficos
Autores principales: Park, Kyemyung, Kim, Yukyung, Son, Mijeong, Chae, Dongwoo, Park, Kyungsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145791/
https://www.ncbi.nlm.nih.gov/pubmed/35631500
http://dx.doi.org/10.3390/pharmaceutics14050914