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Co-Application of Statin and Flavonoids as an Effective Strategy to Reduce the Activity of Voltage-Gated Potassium Channels Kv1.3 and Induce Apoptosis in Human Leukemic T Cell Line Jurkat

Voltage-gated potassium channels of the Kv1.3 type are considered a potential new molecular target in several pathologies, including some cancer disorders and COVID-19. Lipophilic non-toxic organic inhibitors of Kv1.3 channels, such as statins and flavonoids, may have clinical applications in suppor...

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Detalles Bibliográficos
Autores principales: Teisseyre, Andrzej, Chmielarz, Mateusz, Uryga, Anna, Środa-Pomianek, Kamila, Palko-Łabuz, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145895/
https://www.ncbi.nlm.nih.gov/pubmed/35630703
http://dx.doi.org/10.3390/molecules27103227