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MDM2-Mediated Ubiquitination of RXRβ Contributes to Mitochondrial Damage and Related Inflammation in Atherosclerosis

A novel function of retinoid X receptor beta (RXRβ) in endothelial cells has been reported by us during the formation of atherosclerosis. Here, we extended the study to explore the cellular mechanisms of RXRβ protein stability regulation. In this study, we discovered that murine double minute-2 (MDM...

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Detalles Bibliográficos
Autores principales: Zeng, Yi, Cao, Ji, Li, Chun-Xia, Wang, Chun-Yan, Wu, Ruo-Man, Xu, Xiao-Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145909/
https://www.ncbi.nlm.nih.gov/pubmed/35628577
http://dx.doi.org/10.3390/ijms23105766