Binding Properties of RNA Quadruplex of SARS-CoV-2 to Berberine Compared to Telomeric DNA Quadruplex

Previous studies suggest that berberine, an isoquinoline alkaloid, has antiviral potential and is a possible therapeutic candidate against SARS-CoV-2. The molecular underpinnings of its action are still unknown. Potential targets include quadruplexes (G4Q) in the viral genome as they play a key role...

Descripción completa

Detalles Bibliográficos
Autores principales: Oliva, Rosario, Mukherjee, Sanjib, Manisegaran, Magiliny, Campanile, Marco, Del Vecchio, Pompea, Petraccone, Luigi, Winter, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145931/
https://www.ncbi.nlm.nih.gov/pubmed/35628500
http://dx.doi.org/10.3390/ijms23105690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145931/
https://www.ncbi.nlm.nih.gov/pubmed/35628500
http://dx.doi.org/10.3390/ijms23105690

Ejemplares similares