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Binding Properties of RNA Quadruplex of SARS-CoV-2 to Berberine Compared to Telomeric DNA Quadruplex

Previous studies suggest that berberine, an isoquinoline alkaloid, has antiviral potential and is a possible therapeutic candidate against SARS-CoV-2. The molecular underpinnings of its action are still unknown. Potential targets include quadruplexes (G4Q) in the viral genome as they play a key role...

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Detalles Bibliográficos
Autores principales:	Oliva, Rosario, Mukherjee, Sanjib, Manisegaran, Magiliny, Campanile, Marco, Del Vecchio, Pompea, Petraccone, Luigi, Winter, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145931/ https://www.ncbi.nlm.nih.gov/pubmed/35628500 http://dx.doi.org/10.3390/ijms23105690

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