A Structural Comparison of SARS-CoV-2 Main Protease and Animal Coronaviral Main Protease Reveals Species-Specific Ligand Binding and Dimerization Mechanism

Animal coronaviruses (CoVs) have been identified to be the origin of Severe Acute Respiratory Syndrome (SARS)-CoV, Middle East respiratory syndrome (MERS)-CoV, and probably SARS-CoV-2 that cause severe to fatal diseases in humans. Variations of zoonotic coronaviruses pose potential threats to global...

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Detalles Bibliográficos
Autores principales: Ho, Chien-Yi, Yu, Jia-Xin, Wang, Yu-Chuan, Lin, Yu-Chuan, Chiu, Yi-Fang, Gao, Jing-Yan, Lai, Shu-Jung, Chen, Ming-Jen, Huang, Wei-Chien, Tien, Ni, Chen, Yeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145999/
https://www.ncbi.nlm.nih.gov/pubmed/35628479
http://dx.doi.org/10.3390/ijms23105669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145999/
https://www.ncbi.nlm.nih.gov/pubmed/35628479
http://dx.doi.org/10.3390/ijms23105669

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