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A Structural Comparison of SARS-CoV-2 Main Protease and Animal Coronaviral Main Protease Reveals Species-Specific Ligand Binding and Dimerization Mechanism
Animal coronaviruses (CoVs) have been identified to be the origin of Severe Acute Respiratory Syndrome (SARS)-CoV, Middle East respiratory syndrome (MERS)-CoV, and probably SARS-CoV-2 that cause severe to fatal diseases in humans. Variations of zoonotic coronaviruses pose potential threats to global...
Autores principales: | Ho, Chien-Yi, Yu, Jia-Xin, Wang, Yu-Chuan, Lin, Yu-Chuan, Chiu, Yi-Fang, Gao, Jing-Yan, Lai, Shu-Jung, Chen, Ming-Jen, Huang, Wei-Chien, Tien, Ni, Chen, Yeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9145999/ https://www.ncbi.nlm.nih.gov/pubmed/35628479 http://dx.doi.org/10.3390/ijms23105669 |
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