The Reversible Carnitine Palmitoyltransferase 1 Inhibitor (Teglicar) Ameliorates the Neurodegenerative Phenotype in a Drosophila Huntington’s Disease Model by Acting on the Expression of Carnitine-Related Genes

Huntington’s disease (HD) is a dramatic neurodegenerative disorder caused by the abnormal expansion of a CAG triplet in the huntingtin gene, producing an abnormal protein. As it leads to the death of neurons in the cerebral cortex, the patients primarily present with neurological symptoms, but recen...

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Detalles Bibliográficos
Autores principales: Bertapelle, Carla, Carillo, Maria Rosaria, Cacciola, Nunzio Antonio, Shidlovskii, Yulii V., Peluso, Gianfranco, Digilio, Filomena Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146098/
https://www.ncbi.nlm.nih.gov/pubmed/35630602
http://dx.doi.org/10.3390/molecules27103125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146098/
https://www.ncbi.nlm.nih.gov/pubmed/35630602
http://dx.doi.org/10.3390/molecules27103125

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