Comparison of the Effects of Three Dual-Nucleos(t)ide Reverse Transcriptase Inhibitor Backbones on Placenta Mitochondria Toxicity and Oxidative Stress Using a Mouse Pregnancy Model

Nucleos(t)ide reverse transcriptase inhibitors (NRTIs) are the backbone of HIV antiretroviral therapy (ART). ART use in pregnancy has been associated with adverse birth outcomes, in part due to NRTI-induced mitochondrial toxicity. Direct comparison on the effects of commonly used dual-NRTI regimens...

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Detalles Bibliográficos
Autores principales: Balogun, Kayode, Serghides, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146125/
https://www.ncbi.nlm.nih.gov/pubmed/35631648
http://dx.doi.org/10.3390/pharmaceutics14051063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146125/
https://www.ncbi.nlm.nih.gov/pubmed/35631648
http://dx.doi.org/10.3390/pharmaceutics14051063

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