Design of D-Amino Acids SARS-CoV-2 Main Protease Inhibitors Using the Cationic Peptide from Rattlesnake Venom as a Scaffold

The C30 endopeptidase (3C-like protease; 3CL(pro)) is essential for the life cycle of SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) since it plays a pivotal role in viral replication and transcription and, hence, is a promising drug target. Molecules isolated from animals, insects, pl...

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Detalles Bibliográficos
Autores principales: Eberle, Raphael J., Gering, Ian, Tusche, Markus, Ostermann, Philipp N., Müller, Lisa, Adams, Ortwin, Schaal, Heiner, Olivier, Danilo S., Amaral, Marcos S., Arni, Raghuvir K., Willbold, Dieter, Coronado, Mônika A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146215/
https://www.ncbi.nlm.nih.gov/pubmed/35631367
http://dx.doi.org/10.3390/ph15050540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146215/
https://www.ncbi.nlm.nih.gov/pubmed/35631367
http://dx.doi.org/10.3390/ph15050540

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