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Cathepsin B-Cleavable Polymeric Photosensitizer Prodrug for Selective Photodynamic Therapy: In Vitro Studies

Cathepsin B is a lysosomal cysteine protease that plays an important role in cancer, atherosclerosis, and other inflammatory diseases. The suppression of cathepsin B can inhibit tumor growth. The overexpression of cathepsin B can be used for the imaging and photodynamic therapy (PDT) of cancer. PDT...

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Detalles Bibliográficos
Autores principales: Jain, Manish, Bouilloux, Jordan, Borrego, Ines, Cook, Stéphane, van den Bergh, Hubert, Lange, Norbert, Wagnieres, Georges, Giraud, Marie-Noelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146285/
https://www.ncbi.nlm.nih.gov/pubmed/35631388
http://dx.doi.org/10.3390/ph15050564