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SARS-CoV-2 Envelope (E) Protein Binds and Activates TLR2 Pathway: A Novel Molecular Target for COVID-19 Interventions

This paper presents a molecular characterization of the interaction between the SARS-CoV-2 envelope (E) protein and TLR2. We demonstrated that the E protein, both as a recombinant soluble protein and as a native membrane protein associated with SARS-CoV-2 viral particles, interacts physically with t...

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Detalles Bibliográficos
Autores principales: Planès, Rémi, Bert, Jean-Baptiste, Tairi, Sofiane, BenMohamed, Lbachir, Bahraoui, Elmostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146335/
https://www.ncbi.nlm.nih.gov/pubmed/35632741
http://dx.doi.org/10.3390/v14050999