Enhancement of Haloperidol Binding Affinity to Dopamine Receptor via Forming a Charge-Transfer Complex with Picric Acid and 7,7,8,8-Tetracyanoquinodimethane for Improvement of the Antipsychotic Efficacy

Haloperidol (HPL) is a typical antipsychotic drug used to treat acute psychotic conditions, delirium, and schizophrenia. Solid charge transfer (CT) products of HPL with 7,7,8,8-tetracyanoquinodimethane (TCNQ) and picric acid (PA) have not been reported till date. Therefore, we conducted this study t...

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Detalles Bibliográficos
Autores principales: Alamri, Abdulhakeem S., Alhomrani, Majid, Alsanie, Walaa F., Alyami, Hussain, Shakya, Sonam, Habeeballah, Hamza, Alamri, Abdulwahab, Alzahrani, Omar, Alzahrani, Ahmed S., Alkhatabi, Heba A., Felimban, Raed I., Alhabeeb, Abdulhameed Abdullah, Raafat, Bassem M., Refat, Moamen S., Gaber, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146347/
https://www.ncbi.nlm.nih.gov/pubmed/35630772
http://dx.doi.org/10.3390/molecules27103295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146347/
https://www.ncbi.nlm.nih.gov/pubmed/35630772
http://dx.doi.org/10.3390/molecules27103295

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