Vitamin K-Dependent Protein Activation: Normal Gamma-Glutamyl Carboxylation and Disruption in Disease

Vitamin K-dependent (VKD) proteins undergo an unusual post-translational modification, which is the conversion of specific Glu residues to carboxylated Glu (Gla). Gla generation is required for the activation of VKD proteins, and occurs in the endoplasmic reticulum during their secretion to either t...

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Detalles Bibliográficos
Autores principales: Berkner, Kathleen L., Runge, Kurt W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146348/
https://www.ncbi.nlm.nih.gov/pubmed/35628569
http://dx.doi.org/10.3390/ijms23105759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146348/
https://www.ncbi.nlm.nih.gov/pubmed/35628569
http://dx.doi.org/10.3390/ijms23105759

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