Antitumoral Activity of a CDK9 PROTAC Compound in HER2-Positive Breast Cancer

Cyclin-dependent kinases (CDKs) are a broad family of proteins involved in the cell cycle and transcriptional regulation. In this article, we explore the antitumoral activity of a novel proteolysis-targeting chimera (PROTAC) compound against CDK9. Breast cancer cell lines from different subtypes wer...

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Detalles Bibliográficos
Autores principales: Noblejas-López, María del Mar, Gandullo-Sánchez, Lucía, Galán-Moya, Eva M., López-Rosa, Raquel, Tébar-García, David, Nieto-Jiménez, Cristina, Gómez-Juárez, Mónica, Burgos, Miguel, Pandiella, Atanasio, Ocaña, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146359/
https://www.ncbi.nlm.nih.gov/pubmed/35628286
http://dx.doi.org/10.3390/ijms23105476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146359/
https://www.ncbi.nlm.nih.gov/pubmed/35628286
http://dx.doi.org/10.3390/ijms23105476

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