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The E484K Substitution in a SARS-CoV-2 Spike Protein Subunit Vaccine Resulted in Limited Cross-Reactive Neutralizing Antibody Responses in Mice

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), especially emerging variants, poses an increased threat to global public health. The significant reduction in neutralization activity against the variants such as B.1.351 in the serum of convalescent patients and vaccinated people calls f...

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Detalles Bibliográficos
Autores principales: Hu, Longbo, Xu, Yuhua, Wu, Liping, Feng, Jin, Zhang, Lu, Tang, Yongjie, Zhao, Xiang, Mai, Runming, Chen, Liyun, Mei, Lingling, Tan, Yuanzhen, Du, Yingying, Zhen, Yanping, Su, Wenhan, Peng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146450/
https://www.ncbi.nlm.nih.gov/pubmed/35632595
http://dx.doi.org/10.3390/v14050854