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3-(((1S,3S)-3-((R)-Hydroxy(4-(trifluoromethyl)phenyl)methyl)-4-oxocyclohexyl)methyl)pentane-2,4-dione: Design and Synthesis of New Stereopure Multi-Target Antidiabetic Agent

The chiral drug candidates have more effective binding affinities for their specific protein or receptor site for the onset of pharmacological action. Achieving all carbon stereopure compounds is not trivial in chemical synthesis. However, with the development of asymmetric organocatalysis, the synt...

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Detalles Bibliográficos
Autores principales: Sadiq, Abdul, Mahnashi, Mater H., Rashid, Umer, Jan, Muhammad Saeed, Alshahrani, Mohammed Abdulrahman, Huneif, Mohammed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146474/
https://www.ncbi.nlm.nih.gov/pubmed/35630740
http://dx.doi.org/10.3390/molecules27103265