New Quinoline–Urea–Benzothiazole Hybrids as Promising Antitubercular Agents: Synthesis, In Vitro Antitubercular Activity, Cytotoxicity Studies, and In Silico ADME Profiling

A series of 25 new benzothiazole–urea–quinoline hybrid compounds were synthesized successfully via a three-step synthetic sequence involving an amidation coupling reaction as a critical step. The structures of the synthesized compounds were confirmed by routine spectroscopic tools ((1)H and (13)C NM...

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Detalles Bibliográficos
Autores principales: Moodley, Rashmika, Mashaba, Chakes, Rakodi, Goitsemodimo H., Ncube, Nomagugu B., Maphoru, Mabuatsela V., Balogun, Mohammed O., Jordan, Audrey, Warner, Digby F., Khan, Rene, Tukulula, Matshawandile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146500/
https://www.ncbi.nlm.nih.gov/pubmed/35631402
http://dx.doi.org/10.3390/ph15050576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146500/
https://www.ncbi.nlm.nih.gov/pubmed/35631402
http://dx.doi.org/10.3390/ph15050576

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